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Viscoelastic Solution for injection into the articular cavity :
Prefilled syringes of 40 mg/2 ml, in sterile packaging, box unit. Sterilized by steam.
Pain and decreased mobility in degenerative changes and trauma to the knee joint and other synovial joints.
Inject Ostenil Plus into the joint reached once per week, for a total of 1 to 3 injections.
Several joints can be processed simultaneously.
It is possible to repeat treatment cycles if necessary.
In cases of effusion into a joint, it is advisable to reduce the effusion by aspiration, rest, application of a pocket to ice and/or intra-articular injection of a corticosteroid. Treatment with Ostenil Plus will resume in two to three days after.
The content and the external surface of the prefilled syringe Ostenil Plus remain sterile as sterile packaging remains intact. Remove the prefilled syringe from the sterile packaging. Before use, the closure safety of the prefilled syringe must be broken. Break the horizontal piece of the safety shutdown. The tip can be removed with the cap. Attach a right needle (for example 18 to 25 G) and ensure its proper mounting by turning slightly. Before injection, be sure to remove the syringe any air bubbles possibly present.
The synovial fluid, in which the viscoelasticity is related to the presence of hyaluronic acid, which is present in all synovial joints, especially in joints that support weight important, where it allows normal movement and without pain thanks to its lubricating properties and shock absorption. It also ensures the nutritional intake of cartilage. In the case of degenerative joint disorders such as osteoarthritis, the viscoelasticity of the synovial fluid is significantly decreased, resulting in a reduction of the functions of lubrication and shock absorption. This increases the mechanical load of the joint and destruction of cartilage. These phenomena result in a reduced mobility of the joint is achieved and the appearance of pain. Supplementation of the synovial fluid through injections intra-articular hyaluronic acid highly purified, can improve the viscoelastic properties of the synovial fluid. We observe an improvement of the lubricating properties and shock absorption as well as a decrease of the mechanical overload of the joint. As a general rule, the result is a decrease in pain and an improvement in joint mobility which may last for several months after treatment.
Ostenil Plus is a transparent solution of hyaluronic acid natural and highly purified, obtained by bacterial fermentation and devoid of animal protein. Ostenil Plus also contains mannitol, a free radical scavenger, that helps to stabilise the chains of hyaluronic acid. Studies of biocompatibility have shown that Ostenil Plus was well tolerated.
Sodium Hyaluronate 20 mg - Excipients : sodium chloride, monosodium phosphate, disodium phosphate, mannitol, water ppi.